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Pharmaceutical, Biotech & Fine Chemical Production

CD Automation supplies SCR/thyristor power control for pharma, biotech and fine chemical plants - from electric jacketed reactors and hot oil skids to CIP/SIP heaters, WFI systems and cleanroom air heaters.  Our REVO controllers help deliver stable temperature control, support validation activities and improve energy performance across utilities and process equipment.

With REVO C for single zones, REVO-PN for compact multi-zone systems, and REVO-PC, or REVO-DPU zone control on larger skids and furnaces, we integrate easily with PLC, DCS and SCADA systems using common fieldbuses.

    Industry Overview - Electric Heating in Pharmaceuticals & Biotech

    Pharmaceutical, biotech and fine chemical processes rely on accurate temperature control in reactors, dryers, distillation systems and critical utilities such as CIP/SIP and WFI. Electric heating is widely used where precise control, clean operation and fast response are important. Intelligent SCR power control improves stability, supports GMP compliance and helps sites manage their energy use as expectations on efficiency and sustainability continue to rise.

    • Reactors & jacketed vessels
    • CIP/SIP heaters & WFI systems
    • Tray, vacuum & fluid bed dryers
    • Distillation & evaporation systems
    • Hot oil skids & thermal loops
    • Cleanroom duct & inline heaters

    Process Machinery & Applications

    Electrically heated systems commonly controlled with REVO SCR power in pharma, biotech and fine chemical facilities.

    Reactors & Jacketed Vessels

    Electric heating for batch and semi-batch reactors used in synthesis, crystallisation, or neutralisation.
    Common pain points:
    • tight temperature bands
    • ramp/soak control
    • traceability
    Recommended controllers:
    Reactor and jacketed vessel

    CIP / SIP Heaters & WFI Systems

    Electric heaters for clean-in-place, steam-in-place and purified water generation.
    Common pain points:
    • sanitary design
    • temperature stability
    • validation
    Recommended controllers:
    CIP heater and WFI systems

    Tray, Vacuum & Fluid Bed Dryers

    Precision heating for solvent removal and drying of APIs and intermediates.
    Common pain points:
    • uniform drying
    • overheat protection
    • energy control
    Recommended controllers:
    Tray vacuum and fluid bed dryer

    Distillation & Evaporation Systems

    Electric heating of reboilers and evaporators for solvent recovery and purification.
    Common pain points:
    • boil-up stability
    • inrush current
    • power quality
    Recommended controllers:
    Distillation and evaporation system

    Hot Oil Skids & Thermal Loops

    Electric process fluid systems for temperature transfer in multiple reactors or vessels.
    Common pain points:
    • fluid temperature stability
    • loop control
    • energy demand
    Recommended controllers:
    Hot oil skids and thermal loops

    Cleanroom Utilities & HVAC

    Duct and inline heaters for temperature and humidity control in clean environments.
    Common pain points:
    • air stability
    • safety interlocks
    • start-up demand
    Recommended controllers:
    Cleanroom and HVAC white

    Typical Pain Points & How We Solve Them

    • Temperature Control & Product Quality
    API synthesis, crystallisation and drying demand tight temperature control to achieve the right polymorph, yield and impurity profile.
    Solution: REVO C and REVO-PC enable smooth, accurate power control to jacketed reactors, dryers and reboilers, helping maintain narrow operating windows.
    • Validation, Traceability & GMP Compliance
    Pharmaceutical and biotech processes require documented, auditable temperature and utility performance.
    Solution: With REVO C or REVO-PC connected to PLC/SCADA, power and alarm data can be recorded alongside temperature profiles to support GMP and validation documentation.
    • Energy & Utility Efficiency
    CIP/SIP heaters, WFI systems and dryers can be major electrical loads on a site.
    Solution: Demand limiting, staggered starts and appropriate firing modes via REVO-PC or REVO-PN help reduce electrical peaks and improve overall energy performance.
    • Hygiene, CIP/SIP & Cleanroom Constraints
    Equipment in pharma and biotech plants must integrate into hygienic, often space-constrained areas.
    Solution: Compact REVO controllers on skids or in technical areas support cleanroom-friendly designs while keeping power control close to the process.
    • Unplanned Downtime & Maintenance
    Heater or circuit failures in reactors, CIP skids or WFI systems can disrupt production schedules.
    Solution: Diagnostics such as open/partial-load detection and current monitoring help maintenance teams identify failing heaters before they cause lost batches.
    • Electrification & Decarbonisation
    Sites are under pressure to improve energy efficiency and reduce emissions across utilities and process equipment.
    Solution: Electric heaters with modern SCR control offer more precise control than simple on/off and can be integrated into broader energy management strategies.

    Snapshot: Reactor & CIP/WFI Skid Control Upgrade

    Problem: an existing reactor and utility set-up using on/off contactors for jacket heaters and CIP/WFI heaters was struggling with temperature overshoot, slow response and limited data for validation.
    Solution: installation of REVO C on the reactor jacket heater and a REVO-PC master with REVO-C zone control on a new CIP/WFI skid. The reactor and skid heaters are now driven with phase-angle or burst control as appropriate, with power, current and alarm data sent to the site PLC/SCADA over Profinet via the REVO-PC.
    Result: smoother reactor temperature control, improved adherence to CIP/SIP and WFI temperature profiles, reduced nuisance trips and better availability of power data to support validation and energy reporting (typical benefits achievable on similar upgrade projects).

    Why CD Automation?

    • REVO controllers for reactors, utilities and dryers in GMP environments
    • REVO-PC with Modbus, Profinet, EtherCAT into PLC/DCS
    • Firing modes for resistive, variable resistance and transformer-fed loads
    • Support for OEM skid builders and site engineers
    • Retrofit and new-build projects for pharma, biotech and fine chemicals

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